The lack of heat—as is used with EVLT—means no injections of numbing medications along the length of the treated vein, less post-procedure bruising and discomfort, and less potential risk to surrounding nerves or other structures. The tissue adhesive is a formulation of cyanoacrylate that has been used to close vessels in the body for many years. Closure of the vein has been found to be as successful and durable as thermal ablation at the two-year follow-up.